Metabolome Analysis Reveals Potential Mechanisms of Mannan Oligosaccharides to Improve Health, Growth Performance, and Fatty Acid Deposition in Hu Lambs

The effect of mannan oligosaccharides (MOS) on health, growth performance, fatty acids deposition, serum, and urine metabolites, as well the correlation between differential metabolites other indexes, were investigated in Hu lambs. In total, 30 seven-day-old male lambs fed a milk replacer with or without 0.2% MOS (15 each). placed this diet until they 28 days old. significantly increased apparent digestibility organic matter (OM), crude protein (CP), ether extract (EE), calcium (Ca) phosphorus (P), unsaturated acid (UFA) proportion, decreased diarrhea rate saturated (SFA) proportion (p < 0.05). upregulated 20 serum 1 downregulated 11 2 Most these comprised glycerophosphoethanolamines glycerophosphocholines, which are correlated nutrient composition Overall, our results suggest that benefited utilization, profiles via glycerolipid glycerophospholipid metabolism pathways.